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	Provedor de dados Braz. J. Genet. (1) BJMBR (1) Autor Cabello,P.H. (2) Barros,M. (1) Bittencourt,I. (1) Cordovil,I.L. (1) Dolinsky,L.C. (1) Dutra,M.G. (1) Freitas,S.R.S. (1) Lima,A.B. (1) Lopez-Camelo,J.S. (1) Moura-Neto,R.S. (1) Mais... Palavra-chave Congenital malformation (1) Essential hypertension (1) Genetics (1) Polymorphisms (1) Racially mixed populations (1) Renin-angiotensin- aldosterone system (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2007 (1) 1996 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última A simple model for the estimation of congenital malformation frequency in racially mixed populations Braz. J. Genet. Lopez-Camelo,J.S.; Cabello,P.H.; Dutra,M.G.. A simple model is proposed, using the method of maximum likelihood to estimate malformation frequencies in racial groups based on data obtained from hospital services. This model uses the proportions of racial admixture, and the observed malformation frequency. It was applied to two defects: postaxial polydactyly and cleft lip, the frequencies of which are recognizedly heterogeneous among racial groups. The frequencies estimated in each racial group were those expected for these malformations, which proves the applicability of the method. Tipo: Info:eu-repo/semantics/article Palavras-chave: Congenital malformation; Racially mixed populations. Ano: 1996 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400024 Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension BJMBR Freitas,S.R.S.; Cabello,P.H.; Moura-Neto,R.S.; Dolinsky,L.C.; Lima,A.B.; Barros,M.; Bittencourt,I.; Cordovil,I.L.. Essential hypertension is a disease multifactorially triggered by genetic and environmental factors. The contribution of genetic polymorphisms of the renin-angiotensin-aldosterone system and clinical risk factors to the development of resistant hypertension was evaluated in 90 hypertensive patients and in 115 normotensive controls living in Southwestern Brazil. Genotyping for insertion/deletion of angiotensin-converting enzyme, angiotensinogen M235T, angiotensin II type 1 receptor A1166C, aldosterone synthase C344T, and mineralocorticoid receptor A4582C polymorphisms was performed by PCR, with further restriction analysis when required. The influence of genetic polymorphisms on blood pressure variation was assessed by analysis of the odds ratio, while... Tipo: Info:eu-repo/semantics/article Palavras-chave: Essential hypertension; Renin-angiotensin- aldosterone system; Polymorphisms; Genetics. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300005 Registros recuperados: 2 Primeira ... 1 ... Última

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